Search results for "malignant ascites"

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Deterioration in quality of life (QOL) in patients with malignant ascites : Results from a phase II/III study comparing paracentesis plus catumaxomab…

2012

Background: Malignant ascites (MA) is associated with poor prognosis and limited palliative therapeutic options. Therefore, quality of life (QoL) assessment is of particular importance to demonstrate new treatment value. Following the demonstration of the superiority of catumaxomab and paracentesis over paracentesis on puncture-free survival, this analysis aimed at comparing deterioration in QoL between both the treatment options. Patients and methods: In a randomised, multicentre, phase II/III study of patients with MA due to epithelial cell adhesion molecule (EpCAM) positive cancer, the QoL was evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life …

AdultMalemedicine.medical_specialtyRandomizationPalliative careCatumaxomabMedizinlaw.inventionYoung AdultQuality of lifeRandomized controlled triallawAntigens NeoplasmNeoplasmsAscitesAntibodies BispecificmedicineParacentesisHumansParacentesisdeteriorationAgedProportional Hazards ModelsAged 80 and overOvarian Neoplasmsmedicine.diagnostic_testbusiness.industryAscitesmalignant ascitesHematologyOriginal ArticlesMiddle AgedEpithelial Cell Adhesion MoleculeCombined Modality TherapyhumanitiesSurgeryClinical trialOncologyquality of lifeQuality of Life and Supportive CareFemalemedicine.symptombusinessCell Adhesion Moleculesmedicine.drug

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